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David A Walsh Selected Research

Iodoacetic Acid

11/2021Anxiety enhances pain in a model of osteoarthritis and is associated with altered endogenous opioid function and reduced opioid analgesia.
1/2020Peripheral brain-derived neurotrophic factor contributes to chronic osteoarthritis joint pain.
3/2019The impact of anxiety on chronic musculoskeletal pain and the role of astrocyte activation.
1/2019The polyadenylation inhibitor cordycepin reduces pain, inflammation and joint pathology in rodent models of osteoarthritis.
11/2018Analgesic effects of the cathepsin K inhibitor L-006235 in the monosodium iodoacetate model of osteoarthritis pain.
11/2016Robust anti-nociceptive effects of monoacylglycerol lipase inhibition in a model of osteoarthritis pain.
8/2014Osteoprotegerin reduces the development of pain behaviour and joint pathology in a model of osteoarthritis.

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David A Walsh Research Topics

Disease

40Pain (Aches)
11/2022 - 10/2010
18Osteoarthritis
01/2022 - 10/2010
14Inflammation (Inflammations)
11/2022 - 07/2003
9Chronic Pain
03/2022 - 01/2016
9Synovitis
01/2020 - 04/2004
8Rheumatoid Arthritis
01/2020 - 07/2010
6Knee Osteoarthritis
01/2022 - 01/2013
5Arthritis (Polyarthritis)
01/2019 - 08/2006
3Low Back Pain (Lumbago)
01/2022 - 12/2015
2Fatigue
11/2022 - 06/2021
2Neuralgia (Stump Neuralgia)
01/2022 - 01/2018
2Arthralgia (Joint Pain)
01/2020 - 01/2016
2Osteophyte
11/2018 - 08/2014
2Necrosis
10/2017 - 12/2016
2Neurogenic Inflammation
11/2015 - 07/2003
1Hypersensitivity (Allergy)
11/2021
1Migraine Disorders (Migraine)
01/2019
1Sciatica (Sciatic Neuralgia)
10/2017
1Back Pain (Backache)
01/2017
1Hyperalgesia
01/2017
1Experimental Arthritis
01/2016
1Obesity
12/2015
1Foreign Bodies (Foreign Body)
08/2015

Drug/Important Bio-Agent (IBA)

12Analgesics (Analgesic Drugs)IBA
01/2022 - 01/2013
7Iodoacetic AcidIBA
11/2021 - 08/2014
6Nerve Growth Factor (NGF)IBA
01/2019 - 10/2010
5CytokinesIBA
09/2017 - 10/2012
4TropomyosinIBA
01/2020 - 12/2015
4Phosphotransferases (Kinase)IBA
01/2020 - 12/2015
3Non-Steroidal Anti-Inflammatory Agents (NSAIDs)IBA
01/2022 - 01/2020
3Pharmaceutical PreparationsIBA
01/2022 - 11/2018
3Biomarkers (Surrogate Marker)IBA
01/2022 - 01/2019
3Biological ProductsIBA
10/2017 - 10/2014
3Messenger RNA (mRNA)IBA
01/2017 - 04/2004
3CarrageenanIBA
01/2016 - 04/2004
3Substance PIBA
06/2012 - 07/2003
2ametantrone (HAQ)IBA
11/2022 - 01/2020
2Pain-FreeIBA
01/2022 - 03/2019
2Opioid Analgesics (Opioids)IBA
01/2022 - 11/2021
2Capsaicin (Zostrix)FDA Link
01/2021 - 06/2012
2Cathepsin KIBA
11/2018 - 08/2015
2Diphosphonates (Bisphosphonates)IBA
08/2014 - 01/2011
2Antirheumatic Agents (DMARD)IBA
05/2013 - 07/2010
2PPI 2458IBA
09/2011 - 07/2010
2Neurokinin-1 Receptors (Neurokinin 1 Receptor)IBA
04/2004 - 07/2003
1Epoxide HydrolasesIBA
01/2022
114,15-dihydroxyeicosatrienoic acidIBA
01/2022
1Genetic Markers (Genetic Marker)IBA
01/2022
1Morphine (MS Contin)FDA LinkGeneric
11/2021
1LigandsIBA
11/2021
1Serine (L-Serine)FDA Link
11/2021
1Naloxone (Narcan)FDA LinkGeneric
11/2021
1EndorphinsIBA
11/2021
1Ibuprofen (Motrin)FDA LinkGeneric
01/2021
1tanezumabIBA
01/2021
1salicylhydroxamic acid (SHAM)IBA
01/2020
1Brain-Derived Neurotrophic Factor (BDNF)IBA
01/2020
1Glial Fibrillary Acidic ProteinIBA
03/2019
1Tartrate-Resistant Acid PhosphataseIBA
01/2019
1mRNA Cleavage and Polyadenylation FactorsIBA
01/2019
12'-deoxyadenosineIBA
01/2019
1cordycepinIBA
01/2019
1amsonic acid (DAS)IBA
12/2018
1CRA 013783IBA
11/2018
1Adalimumab (Humira)FDA Link
10/2017
1AntibodiesIBA
10/2017
1Freund's AdjuvantIBA
01/2017
1Duloxetine Hydrochloride (Cymbalta)FDA Link
01/2017
1Adrenal Cortex Hormones (Corticosteroids)IBA
01/2017
1Monoacylglycerol LipasesIBA
11/2016
1EndocannabinoidsIBA
11/2016
1MonoglyceridesIBA
11/2016
1Lipase (Acid Lipase)FDA Link
11/2016
1MJN110IBA
11/2016
1Prostaglandin-Endoperoxide Synthases (Cyclooxygenase)IBA
04/2016
1Long Noncoding RNAIBA
04/2016
1RNA (Ribonucleic Acid)IBA
04/2016
1incomplete Freund's adjuvantIBA
01/2016
1CollagenIBA
01/2016
1Collagen Type II (Type II Collagen)IBA
01/2016
1trkA ReceptorIBA
01/2016
1Calcitonin Gene-Related PeptideIBA
11/2015
1Calcitonin Gene-Related Peptide Receptor AntagonistsIBA
11/2015
1Proteoglycans (Proteoglycan)IBA
11/2014
1Immunomodulating AgentsIBA
10/2014

Therapy/Procedure

5Therapeutics
05/2022 - 01/2014
5Knee Replacement Arthroplasty (Total Knee Replacement)
03/2022 - 11/2014
5Replacement Arthroplasty
01/2022 - 12/2012
5Intra-Articular Injections
01/2020 - 07/2010
3Injections
10/2017 - 12/2015
2Pain Management
05/2022 - 01/2015
2Analgesia
11/2021 - 09/2017
2Biological Therapy
10/2017 - 12/2012
1Activities of Daily Living (ADL)
01/2019
1Aftercare (After-Treatment)
01/2019
1Subcutaneous Injections
10/2017
1Conservative Treatment
01/2017
1Intradermal Injections
01/2016
1Orthopedic Procedures
05/2015
1Length of Stay
05/2015